Minor Groove Binder MGB is a class of molecules that selectively bind to the minor groove of double stranded DNA. A common structure is a dihydrocyclopyrrolo tripeptide derivative. When MGB is attached to the 3 prime end of a probe it significantly enhances the binding stability between the probe and the target sequence.

Based on optimized synthesis processes and an upgraded quenching system Synbio Technologies has developed a new generation of optimized MGB probes.

• Improved signal intensity

• Significantly reduced background fluorescence

• Enhanced amplification curve stability

• Improved SNP discrimination capability

• Compatibility with major qPCR detection platforms

Trial Details

We are offering 20 free samples (2 OD per sample) on a first-come, first-served basis. This is an opportunity to perform a direct performance comparison against your current probes.

This trial is ideal for:

Researchers currently conducting qPCR experiments.

Scientists who have faced suboptimal results with their current probes and wish to conduct a comparative test. Priority will be given to those looking to verify performance improvements.

Apply for Your Free Trial

Secure one of the 20 limited spots to test our Enhanced MGB Probes.

Contact Us

Learn More About MGB Probe Technology

For a deeper dive into the principles and advantages of MGB probes, please visit our blog.

(How to Choose qPCR Probes? A Detailed Overview of MGB Probe Technology)

Explore Our Products and Services

For more information on our comprehensive suite of synthetic biology solutions, please visit our main website.