The General Introduction of siRNA/miRNA Synthesis
RNA interference (RNAi) is a powerful gene silencing tool, crucial for biological and therapeutic research, especially in targeting undruggable diseases like cancer. siRNA binds to target mRNA in the RISC complex to inhibit its function, while miRNAs regulate mRNA degradation or translation, with dysregulation linked to cancer.
Synbio Technologies offers highly customized siRNA and miRNA synthesis services, ensuring high-quality products through expert synthesis techniques and rigorous quality controls. In addition, Synbio Technologies provides various chemically modified siRNAs for enhanced stability and efficacy, as well as various miRNA products, including mimics, inhibitors, and controls, to support diverse research needs.
Highlights
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- Provide Diversified siRNA & miRNA Products
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- Expert Technical Team to Provide Support
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- Strictly Confidential Project Details
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- Strict Quality Control to Avoid Contamination
Service Details
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Products name
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Yield
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Purification
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Turnaround Times
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Price
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siRNA NC FAM
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2.5 nmol
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HPLC/OPC
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6-15 BD
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Starting from $56
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siRNA NC
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2.5 nmol
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siRNA
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Starting from 2.5 nmol
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Modified or fluorescence labeled siRNA (2-OMe, Thiol, Chol, Biotin, FAM, Cy5, Cy3, etc)
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Quote
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Quote
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* For more information please contact us at quote@synbio-tech.com.
Synbio Technologies also provides a guaranteed siRNA service. The three/four designed and delivered siRNA ensure at least one siRNA can effectively inhibit the expression of the target gene. The resulting inhibition efficiency will be at least 70% (The transfection efficiency will be at least 90%).
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Products
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Yield
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Purification
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Turnaround Times
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Price
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3 siRNAs
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5 nmol
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HPLC/OPC
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6-9 BD
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$249
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siRNA NC FAM
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2.5 nmol
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siRNA NC
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2.5 nmol
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Positive siRNA control
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2.5 nmol
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Transfection reagents
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100 μL
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Products
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Yield
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Purification
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Turnaround Times
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Price
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4 siRNAs
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5 nmol
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HPLC/OPC
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6-9 BD
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$299
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siRNA NC FAM
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2.5 nmol
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siRNA NC
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2.5 nmol
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Positive siRNA control
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2.5 nmol
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Transfection reagents
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100 μL
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* For more information please contact us at quote@synbio-tech.com.
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Products
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Yield
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Purification
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Turnaround Times
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Price
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miRNA mimics NC FAM
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2.5 nmol
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HPLC/OPC
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3-5 BD
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Starting from $56
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miRNA mimics NC
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2.5 nmol
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miRNA mimics
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5 nmol
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miRNA inhibitors NC FAM
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2.5 nmol
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miRNA inhibitors NC
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2.5 nmol
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miRNA inhibitor
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5 nmol
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miRNA agomirs
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2.5 nmol
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miRNA antagomirs
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2.5 nmol
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* For more information please contact us at quote@synbio-tech.com.
Deliverables
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Lyophilized RNA
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Certificate of Analysis (COA)
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QC Report (MS/HPLC)
FAQs
Specificity: Ensure that the siRNA sequence specifically targets the target gene to avoid off-target effects.
Effectiveness: Screen siRNA sequences with high silencing efficiency.
Stability: Optimize the siRNA sequence to improve its stability and effectiveness in the cell.
qPCR: Quantitatively detect changes in mRNA levels of target genes.
Western Blot: Detect the expression level of the protein encoded by the target gene.
Fluorescence Microscopy: Observe the distribution and expression of siRNA or shRNA in cells by fluorescent labeling.
RNA oligos should be stored at -20°C or lower in RNase-free water or specialized RNA storage solutions to prevent degradation. Avoid repeated freeze-thaw cycles during storage to maintain their integrity.
Resources
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