Synbio Technologies provides a fast and convenient standard DNA oligo synthesis. Large scale and bulk custom DNA oligos can be ordered with identical high purity, competitive prices, and fast turnaround time.
Standard Oligo Synthesis (Price per Base)
|
Synthesis Scale
|
10nm
|
25nm
|
50 nmol
|
100 nmol
|
200 nmol
|
1 μmol
|
11-59nt
|
$0.07
|
$0.10
|
$0.15
|
$0.30
|
$0.40
|
$1.00
|
60-90nt
|
$0.08
|
$0.12
|
$0.18
|
$0.35
|
$0.50
|
$1.20
|
* Longer oligos, 96/384 plate batch oligos or other large scale synthesis are available, please contact us for a quote.
* Please refer to the purification table for the final output corresponding to different synthesis scale.
Purification (Price per Oligo)
|
11-59nt
|
Purification Method
|
Synthesis Scale
|
10nm
|
25nm
|
50 nmol
|
100 nmol
|
200 nmol
|
1 μmol
|
DSL
|
Final Yield
|
1 OD / 5 nmol
|
2 OD / 10 nmol
|
5 OD / 25 nmol
|
10 OD / 50 nmol
|
15 OD / 75 nmol
|
50 OD / 250 nmol
|
Price
|
Free
|
Free
|
Free
|
Free
|
Free
|
Free
|
PAGE Plus
|
Final Yield
|
–
|
–
|
2 OD / 10 nmol
|
5 OD / 25 nmol
|
10 OD / 50 nmol
|
30 OD / 150 nmol
|
Price
|
–
|
–
|
$5.00
|
$5.00
|
$5.00
|
$5.00
|
PAGE
|
Final Yield
|
–
|
–
|
–
|
2 OD / 10 nmol
|
5 OD / 25 nmol
|
10 OD / 50 nmol
|
Price
|
–
|
–
|
–
|
$15.00
|
$15.00
|
$30.00
|
HPLC
|
Final Yield
|
–
|
–
|
–
|
2 OD / 10 nmol
|
5 OD / 25 nmol
|
10 OD / 50 nmol
|
Price
|
–
|
–
|
–
|
$10.00
|
$10.00
|
$20.00
|
60-90nt
|
DSL
|
Final Yield
|
1 OD / 1.5 nmol
|
2 OD / 3 nmol
|
5 OD / 7.5 nmol
|
10 OD / 15 nmol
|
15 OD / 22.5 nmol
|
50 OD / 75 nmol
|
Price
|
Free
|
Free
|
Free
|
Free
|
Free
|
Free
|
PAGE Plus
|
Final Yield
|
–
|
–
|
2 OD / 3 nmol
|
5 OD / 7.5 nmol
|
10 OD / 15 nmol
|
30 OD / 45 nmol
|
Price
|
–
|
–
|
$5.00
|
$5.00
|
$5.00
|
$5.00
|
PAGE
|
Final Yield
|
–
|
–
|
–
|
2 OD / 3 nmol
|
5 OD / 7.5 nmol
|
10 OD / 15 nmol
|
Price
|
–
|
–
|
–
|
$15.00
|
$15.00
|
$30.00
|
HPLC
|
Final Yield
|
–
|
–
|
–
|
2 OD / 3 nmol
|
5 OD / 7.5 nmol
|
10 OD / 15 nmol
|
Price
|
–
|
–
|
–
|
$10.00
|
$10.00
|
$20.00
|
* The total price of oligo=price/base*nt + purification price.
* If you need other synthesis scale and lengths, please contact us for a
quote.
* For modified oligos please click Oligo Modification & Labeling.
Synbio Technologies can provide customers with economized micro-scale oligo synthesis services including the custom synthesis of phosphoric acid, amino, biotin, and other modifications.
Length
|
Final Yield
|
Purification
|
Turnaround Time/Price
|
Deliverables
|
15-90nt, no fewer than 96 oligos
|
0.1-1 nmol
|
Desalt or PAGE Plus
|
Quote
|
Plate delivery or pool delivery
|
Synbio Technologies provides mass production of oligos with high purity in measurements from milligrams to grams. These oligos are mainly used in kit development, drug discovery (ASOs drugs), aptamers, DEL (DNA encoded compound library), IVD research fields, etc.
Large-Scale Oligo Synthesis(Unmodified DNA Price)
|
Final Yield
|
10–25 nt
|
26–40 nt
|
41–55 nt
|
>55 nt
|
25 mg
|
$1,338
|
$1,451
|
$1,761
|
Quote
|
50 mg
|
$1,427
|
$1,524
|
$1,797
|
100 mg
|
$1,587
|
$1,761
|
$2,119
|
200 mg
|
$1,693
|
$1,949
|
$3,208
|
250 mg
|
$1,787
|
$2,042
|
$2,480
|
500 mg
|
$2,383
|
$2,795
|
$3,438
|
1 g
|
$4,289
|
$4,714
|
$5,642
|
*If you need to know the turnaround time and the price of modified DNA oligos, please contact us for a quote.
Purification
|
QC Analysis
|
Deliverables
|
Modifications and Probes
|
Backbone
|
Linker
|
qPCR Probes
|
HPLC/ PAGE
|
● HPLC/LC-MS
● Endotoxin Control/Bioburden (optional)
|
● Lyophilized products
● COA file
|
● Phosphorothioate
● 2’F-RNA
● 2′-O-Methyl
● MOE-RNA
● LNA
|
● Amino
● Biotin
● Thiol
● Digoxigenin
● Acrydite
● DBCO
● Azide
|
● MGB Probe
● BHQ Probe
● Dabcyl Probe
● TAMRA Probe
|
Synbio Technologies provides both the design and synthesis of these degenerate primers, which reduce the deviation inherent in the synthesis procedures and realize the accurate proportional control.
Symbol
|
Base Type
|
Standard Ratio
|
Price
|
Standard Level
|
Superior Level
|
R
|
A,G
|
50% : 50%
|
Quote
|
Quote
|
Y
|
C,T
|
50% : 50%
|
M
|
A,C
|
50% : 50%
|
K
|
G,T
|
50% : 50%
|
S
|
C,G
|
50% : 50%
|
W
|
A,T
|
50% : 50%
|
H
|
A,C,T
|
33% : 33% : 33%
|
B
|
C,G,T
|
33% : 33% : 33%
|
V
|
A,C,G
|
33% : 33% : 33%
|
D
|
A,G,T
|
33% : 33% : 33%
|
N
|
A,C,G,T
|
25% : 25% : 25% : 25%
|
* Non-standard base proportions should be declared clearly, for example, N(20%A:30%C:40%G:10%T).
Synbio Technologies’ Oligo Synthesis Platform utilizes an optimized ultra-long chain design and synthesis program to meticulously monitor and control the synthesis process. This process allows us to generate long high-quality oligos (90-129 mer) and even ultra-long oligos (130-150 mer) according to individual requests.
Length
|
Quantity
|
Purification
|
Turnaround TIme
|
Price
|
90-109 mer
|
1 OD
|
PAGE / Dual-PAGE
|
5-6 business days
|
Quote
|
110-129 mer
|
1 OD
|
5-7 business days
|
130-150 mer
|
0.5 OD
|
5-8 business days
|