Standard Animal Genome KO Libraries|Synbio Technologies

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General Introduction of Standard Animal Genome KO Libraries

Animal genetic screening is useful for studying molecular mechanisms that influence growth, reproduction, disease resistance, meat quality, and other key traits. Additionally, genetic screening enhances prevention and treatment strategies for viral infection. The gene screening system provides a large-scale, multi-dimensional tool for molecular breeding.

Synbio Technologies uses the genetic blueprints of sheep, rabbits, pigs, dogs, and cattle to develop its Genome knockout libraries. These libraries come in single- or dual-vector systems with puro selectable markers and can be packaged with lentiviruses for efficient cell transfection and screening. By providing Genome libraries for species beyond humans and mice, our animal Genome knockout libraries address a market gap and enhance the use in molecular breeding, regenerative medicine, and research on animal models of human diseases.

Highlights

High Target Activity and Low Off-target Rate sgRNA Sequences
Easy Cell Delivery and Screening Achieved
High Edit-efficient Genome KO Libraries
>99.9% Library Coverage, >80% Accuracy, and <10 Uniformity

Service Details

Catalog	Product Name	Sequence Information	Amount	Price
STCRI100088	Syno Sheep Genome Knockout Libraries	20,400 targeted genes, 118,626 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote
STCRI100100	Syno Rabbit Genome Knockout Libraries	19,669 targeted genes, 77,192 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote
STCRI100137	Syno Dog Genome Knockout Libraries	19,523 targeted genes, 77,440 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed. 40,779 sgRNA sequences targeted lncRNA	200 μg	Quote
STCRI100115	Syno Pig Genome Knockout Libraries	20,823 targeted genes, 119,719 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote
STCRI100124	Syno Cattle Genome Knockout Libraries	21,698 targeted genes, 130,015 sgRNA sequences and 2,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote

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FAQs

Can you customize other animal libraries?

Synbio Technologies’ sgRNA designs are not limited to species, other animal libraries can be customized upon request.

What applications can animal genome-wide knockout libraries be used for?

Animal genome-wide knockout libraries can be used for various applications, including: Breeding for Disease Resistance: These libraries allow for screening host factors linked to viral infections, such as PDCoV and ASFV, to identify new targets for developing antiviral genetically modified animals.
Disease Research: They help in understanding the mechanisms of viral infections by identifying host factors involved, leading to the discovery of effective preventive and control measures.