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Animal Genome KO Libraries

Animal genetic screening is helpful to study the molecular mechanisms related to their growth, reproduction, disease, and other key traits. In addition, genetic screening also improves the prevention and treatment strategies against viral infection. The gene screening system provides a large-scale and multi-dimensional screening tool for molecular breeding.

Synbio Technologies harnesses the genetic blueprints of sheep, rabbit, pig, dog, and cattle to build a series Genome knockout libraries. These libraries are single- or dual-vector systems with Puro selectable markers that can be packaged with lentiviruses for cell transfection and screening. Our animal Genome knockout libraries fill the gap of Genome KO libraries for species other than human and mouse on the market, expanding the application of Genome KO in molecular breeding, regenerative medicine, and animal research.

Highlights

Accurate sgRNA Design
Ease to Use Format
Highly Editing-efficient Genome KO Libraries for Late-stage Screening
The Coverage of the Constructed Library is > 99.9%, the Accuracy > 80%, and the Uniformity < 10.

Product List

Catalog	Product Name	Sequence Information	Amount	Price
STCRI100088	Syno Sheep Genome Knockout Libraries	20,400 targeted genes, 118,626 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote
STCRI100100	Syno Rabbit Genome Knockout Libraries	19,669 targeted genes, 77,192 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote
STCRI100137	Syno Dog Genome Knockout Libraries	19,523 targeted genes, 77,440 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed. 40,779 sgRNA sequences targeted lncRNA	200 μg	Quote
STCRI100115	Syno Pig Genome Knockout Libraries	20,823 genes are targeted, 119,719 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote
STCRI100124	Syno Cattle Genome Knockout Libraries	21,698 targeted genes, 130,015 sgRNA sequences and 2,000 control (non-targeted) sgRNA sequences designed.	200 μg	Quote

Workflow

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FAQs

Can you customize other animal libraries?

Yes,Synbio Technologies’s sgRNA design are not limited to any species

What applications can animal genome-wide knockout libraries be used for?

Animal genome-wide knockout libraries can be used for various applications, including: Breeding for Disease Resistance: These libraries allow for screening host factors linked to viral infections, such as PDCoV and ASFV, to identify new targets for developing antiviral genetically modified animals.
Disease Research: They help in understanding the mechanisms of viral infections by identifying host factors involved, leading to the discovery of effective preventive and control measures.