At Synbio Technologies we offer a unique approach to gene synthesis services through our revolutionary Syno Gene Synthesis Platform. This three phase platform allows us to generate any customer specified genetic sequence in text format, up to and including 150 Kb in length. The requested sequences can vary greatly in both length and structure. For example, a requested sequence can contain a gene with a deleterious mutation in order to induce a debilitating effect, rendering the gene inactive in order to study the phenotypic effects. Or the requested sequence can be one not previously existing within nature, in order to study the effects of evolution or antibiotic resistance. These examples are made possible through Synbio Technology’s various gene synthesis services. First, our Syno^® 2.0 Gene Synthesis plays a large role in small gene/short sequence synthesis. The Syno^® 2.0 Gene Synthesis platform may be meant for short sequence synthesis, but it still has the capabilities and confidence of generating sequences with extreme accuracy of up to and including 150 Kb in length. Second, our Syno^® 3.0 Next Generation Gene Synthesis Platform is a groundbreaking piece of technology that allows us to synthesize sequences that span near the length of small genomes. This gene synthesis services allows us to generate sequences up to an including 150 Kb in length, which was previously thought to be impossible to successfully and accurately engineer in a laboratory setting. With these two gene synthesis services, along with a wide range of other biological technology services, Synbio Technology is ready to supply our customers with the highest quality product within an efficient timeframe. This confidence starts with one of our most successfully gene synthesis services, the Syno^® 2.0 Platform.

The Syno^® 2.0 Gene Synthesis Platform is one of the corner stones of our gene synthesis services. This platform has various specializations in gene synthesis such as: pathway synthesis, small genome synthesis, vector construction, and codon optimization technology. With this platform, we are able to successfully and accurately synthesize the customer specified sequence of interest with one hundred percent accuracy. This is accuracy and confidence in sequence validity comes from the multiple occasions in which we use Sanger sequencing to verify the sequence being generated. In addition to the high quality sequence synthesis, we offer cloning of each prepared sequence to ensure the customer is provided with the adequate amount of product. Before each sequence is amplified, it is verified again with Sanger sequencing to verify the accuracy of the sequence. In addition to the specializations Syno^® 2.0 offers, this platform also offers the ability to generate various structures of DNA commonly utilized in various fields of genetics research. Some of these structures include: hairpin structures, repeated sequences, high GC content regions, high AT content regions, or multiple consecutive nucleotide sequences. All of these structures offer a unique approach to studying various topics within the field of genetics. With the Syno^® 2.0 Platform, and our other gene synthesis services, Synbio Technologies is ready to offer our customers a unique approach to conducting genetic research.

The Syno^® 3.0 Next Generation Gene Synthesis Platform differs slightly from the Syno^® 2.0 Platform, and our other gene synthesis services, but the output is still guaranteed to be one hundred percent accurate with a low price and fast turnaround time. The Syno^® 3.0 Platform specializes in ChipBased DNA synthesis, CRISPR-Cas9 Libraries, and digital information storage. In other words, the Syno^® 3.0 Platform is one of our gene synthesis services that offer a large amount of generated sequences to be synthesized. The chip-based gene synthesis approach allows us to generate thousands upon thousands of sequences all within a single chip. This allows for rapid production of sequences with high accuracy when multiple chips are used. The generated sequences are then, of course, verified with Sanger sequencing to guarantee one hundred percent accuracy. This method is used to generate large genes, up to and including 150 Kb in length with one hundred percent accuracy. In addition to this, the Syno^® 3.0 platform gene synthesis services that Synbio Technologies offers, is the use of and experience with CRISPR-Cas9. Ever since the discovery and first successful utilization of CRISPR-Cas9, in 1993, it has been used time and time again in order to conduct genome edits. CRISPR-Cas9 has become one of the most popular and effective methods in order to conduct genome edits. This gene synthesis service offers CRISPR-Cas9 based gene knockout-out, gene knock-in, transcription activation, and transcription inhibition. All of these applications are methods of altering the expression level of a particular sequence/gene of interest. This alteration of expression will then be applied to various types of genetics research.

All of the gene synthesis services, as much as they vary in application, offered by Synbio Technologies have been tested and proven to be one hundred percent effective. This comes in the form of our guaranteed sequence validation, through Sanger sequencing. This accuracy and validity have given Synbio Technologies a reputation as one of the premier companies in the gene synthesis industries. This reputation relies heavily on our Syno^® Gene Synthesis Platform. With this gene synthesis service platform, we are able to synthesize the sequence/gene of interest with extreme accuracy in a cost effective manner. This cost effective manner, on top of the efficient turnaround time, we at Synbio Technologies are ready to supply our customers with the highest quality product for the lowest prices.

Gene Synthesis Related Services

• Codon Optimization
• Vector Construction
• Small Genome Synthesis
• Pathway Synthesis