Genetic screening of livestock and poultry is helpful to study the molecular mechanisms related to their growth, reproduction, disease, meat quality, and other key traits. In addition, genetic screening also improves the prevention and treatment strategies against viral infection. The CRISPR gene screening system provides a large-scale and multi-dimensional screening tool for molecular breeding.
Synbio Technologies selects chicken, duck, sheep, rabbit, pig, and dog genomes to construct its CRISPR knockout library. These libraries are single- or dual-vector systems with Puro selectable markers that can be packaged with lentiviruses for cell transfection and screening. Our livestock and poultry genome CRISPR knockout libraries fill the gap of CRISPR libraries for species other than human and mouse on the market, expanding the application of CRISPR in molecular breeding, regenerative medicine, and animal-based human disease research.