Synbio Technologies’ state-of-the-art CPG ODNs service line, offers advanced Oligodeoxynucleotides that facilitate targeted gene modulation with precision and ease. Our experienced team of experts has developed a highly specialized manufacturing process that produces fully modified CPG ODNs with high purity and excellent stability.
We understand the importance of gene expression modulation in biological research, and our CPG ODNs are the perfect solution for your needs. These ODNs are specially designed to induce potent immune responses and elicit antiviral and antitumor effects, making them ideal candidates for use in cutting-edge research endeavors.
Our manufacturing process involves fully modifying the CPG ODNs with selective and precise chemical modifications that enhance their stability and immunostimulatory effects.
What sets us apart from other suppliers is our dedication to quality. Our CPG ODNs are rigorously tested and undergo strict quality control measures to ensure that our customers receive a robust product that is both reliable and effective.
With our CPG ODNs, you can conduct your research with confidence, knowing that you are using a top-of-the-line product that delivers consistent results. Our team is always available to provide support and guidance, ensuring that you have all the tools you need for your work.
At Synbio Technologies, we offer a range of CpG ODNs that are classified into three distinct classes; Class A, B, and C. Each class boasts unique structural characteristics and immune effects suited for different applications.
Class A CpG ODNs possess a palindromic sequence made up of a CpG dinucleotide, poly G tails at both ends, and partial phosphorothioate modifications on the phosphodiester bond skeleton. The palindrome sequence and poly G tail create a high-level structure that activates plasmocytoid dendritic cells and induces a significant amount of type I interferons. However, this class only elicits a weak response in B cells.
Class B CpG ODNs are linear and fully modified with phosphorothioates. They possess strong immunostimulatory activity on B cells but fail to activate plasmocytoid dendritic cells.
Class C CpG ODNs are also fully modified with phosphorothioates, yet they differ from class B due to their ability to form dimers via the palindromic sequence. Consequently, they possess the activity of both class A and class B CpG ODNs, making them highly versatile as they activate both plasmocytoid dendritic cells and B cells.
We provide these three classes of CpG ODNs for various species, ensuring that our clients have a complete solution for their research needs. Whether your research requires activation of plasmacytoid dendritic cells or strong immune responses in B cells, we have the right CpG ODN for you. Trust us to provide you with CpG ODNs that will help you reach your research goals.
Choose SynBio Technologies’ CPG ODNs service line for your next research project and experience the difference that precision and quality make. Contact us today to learn more!