Oligonucleotide synthesis is the chemical synthesis of short nucleic acid fragments with defined sequence. In this process, 2 ‘- deoxynucleosides (dA, dC, dG and dT), ribonucleosides (A, C, G and U) or chemically modified nucleosides (such as LNA) are synthesized by solid-phase phosphoramide method to obtain sequences with specific chemical structure and function. Oligonucleotide synthesis has the characteristics of stable, efficient and rapid synthesis, usually in the form of primers or probes, widely used in PCR amplification, DNA sequencing, molecular diagnosis and many other fields.
Synbio Technologies’ oligonucleotide synthesis platform equips state-of-the-art synthesizers and leading professional teams experienced in the oligo synthesis as well as modification technologies. This allows us to provide high-quality oligo products to scientific researchers and industrial customers around the world. By leveraging our advanced and innovative manufacturing process, Synbio Technologies offers a wide range of oligonucleotide synthesis options, including custom DNA oligos, diagnostic oligos & probes, NGS oligos, modified oligos, antisense oligos, CpG ODNs, etc. In addition, we also provide high-throughput oligo library and oligo pool synthesis to customers with large-scale oligo projects. Synbio Technologies is always competent to offer tailor-made approached to accomplish every request to oligo synthesis.
Standard Oligo Synthesis Process
Based on customers’ various requests, Synbio Technologies’ scientific teams will performance proprietary DNA sequence analysis and design. CpG-based chemical oligo synthesis will be finished by utilizing industry leading manufacture process. For final sequence verification, MS analysis and other stringent quality control method will be conducted step by step.