With the continuous advancement of RNA technologies such as siRNA, miRNA, and RNA aptamers, RNA research is now shifting towards larger and more complex RNA molecules, including long non-coding RNA (lncRNA). This area of research has led to an increased demand for long RNA synthesis services that can synthesize RNA molecules up to 300 nucleotides in length. LncRNA, as an example, plays a crucial role in regulating gene expression levels at multiple levels and is involved in many key regulatory processes.
lncRNA is a class of RNA molecules that have a transcript length exceeding 200 nucleotides. Unlike messenger RNA (mRNA), they do not code for proteins. Instead, they play a crucial role in regulating gene expression levels at multiple levels, including epigenetic regulation, transcriptional regulation, and post-transcriptional regulation.
Recent studies have revealed that lncRNA molecules play significant roles in many essential regulatory processes, such as X-chromosome silencing, genomic imprinting, chromatin modification, transcriptional activation, transcriptional interference, and intranuclear transport. These regulatory functions of lncRNA have attracted widespread attention from the scientific community.