Synbio Technologies offers high quality DNA libraries of any size and complexity with an efficient time frame and at industry’s most competitive rate. Our synthetic DNA libraries are designed by an experienced bioinformatics team to facilitate various research applications, including functional genetics, directed evolution, protein engineering and antibody studies.
Why Us?
Proprietary synthesis platforms guarantee the successful synthesis of multiple libraries.
High quality libraries can be accurately synthesized with large capacity (up to 1014 variants), coverage rate>95%, uniformity index<10.
Flexible deliverables: oligo pools, PCR fragments, pooled plasmids, plasmid arrays, etc.
Service Specifications
| Length (nt/bp) | Complexity Analysis | Diversity Analysis by Sequencing | Delivery Time (Business Days) |
Price | Deliverables |
|---|---|---|---|---|---|
| Site-Saturation Mutagenesis Library, eg.NNK Library | √ | √ | 20-40 | Quote | 10 μg linear random PCR product library (up to 1011 randomly mutated molecules) or 50-1000 ug plasmid. |
| Combinatorial Mutagenesis Library, eg.Trimer Library | √ | √ | 20-40 | Quote | |
| Modular Substitution Library | √ | √ | 20-40 | Quote |
Library Types
| Library Type | Description | Schema |
|---|---|---|
| Alanine Scan Library | Research on amino acid residues critical to protein function, interaction, and shape by replacing an individual amino acid with alanine at every position. |  |
| Site-Saturation Mutagenesis Library | Mutate only one site at a time within a sequence, it can be substituted to all 20 possible amino acids or specified codons. |  |
| Combinatorial Mutagenesis Library | Mutate multiple sites within a sequence, it can be defined by customer desired amino acid types and ratios at each site. |  |
| Antibody Library | Create a high diversity synthetic antibody library or improve existing antibody functionality such as specificity, immunogenicity, affinity, expression, and/or aggregation. |  |
| Modular Substitution Library | Build new genetic modules, regions or pathways from DNA parts including regulatory elements and/or coding sequences. |  |
| CRISPR Library | Customized CRISPR library and human genome CRISPR knockout library meet the screening needs of different customers. |  |
Related Services
Next Generation Gene Synthesis
High throughput and most cost-effective.
DNA synthesis platform, starts at $0.09/bp for synthesis.
Vector Construction
shRNA, TALEN, CRISPR-Cas9 vector construction and validation.
DNA Sequencing & Gene Analysis
High quality standard present reliable gene sequencing and analysis services.
Protein Expression & Purification
Guaranteed 3 mg protein of 85% purity with our Syno® Gene to Protein Package in E. coli expression system.
