Codon optimization is a method referring to the use of preferred codons for a particular organism. The purpose is to avoid the rare codons with low utilization rate in the organism, to adjust the GC content, to simplify mRNA’s secondary structure after gene transcription, and to remove the motif which is not conducive to efficient expression and add the helpful ones. The commercialization of gene synthesis over traditional PCR cloning has greatly promoted the application scope and influence of codon optimization.
By the employment of NG Codon system, Synbio Technologies’ patent pending codon optimization algorithm, complex sequences are optimized efficiently in order to achieve a significantly higher protein expression level. Codon optimization service is complimentary to standard gene synthesis service. The codon optimization platform takes into consideration the below factors: