In the field of genetic research, one of the most exciting developments in recent years has been the advent of gene synthesis. This revolutionary technology allows scientists to construct physical genetic sequences from requested sequences in text format – in other words, to create brand new genes that do not exist in nature. Gene synthesis has opened up new avenues of research and made it possible to explore aspects of genetics that were previously inaccessible. At Synbio Technologies, we are proud to be at the forefront of this exciting field, with our state-of-the-art Syno Platform for large gene synthesis.

What is large gene synthesis, and why is it so important? Essentially, large gene synthesis is the process of creating genes that are much longer than the average gene found in nature. While most genes in the human genome are less than 10,000 base pairs long, large genes can be up to 150,000 base pairs in length. This makes them a valuable tool for researchers, as they can be used to study complex traits and diseases that involve multiple genes, as well as to create entirely new genetic structures for therapeutic or industrial purposes.

There are two main methods of large gene synthesis: the Gibson Assembly Method and yeast homologous recombination technology. While both methods have their advantages, we have found that yeast homologous recombination technology is the most reliable and efficient option for large gene synthesis. This technology is capable of assembling gene fragments up to 1.08 Mb in length, which makes it a powerful tool for creating genes of any length. At Synbio Technologies, we use our Syno® 2.0 and Syno® 3.0 platforms, which are built around yeast homologous recombination technology, to provide one-stop services for basic gene synthesis, gene cluster creation, and large gene synthesis.

When it comes to large gene synthesis, accuracy is key. That’s why we offer 100% sequence verification on all of our large gene synthesis products. Our Syno® Platform uses Sanger sequencing at multiple stages of the synthesis process to ensure that the sequence is accurate and matches the requested sequence exactly. This level of accuracy is essential for large gene synthesis, as the complexity and length of the genes can make errors more likely. By offering this level of quality control, we are able to provide our customers with a reliable and accurate product that can be used with confidence in their research.

In addition to our commitment to accuracy, we are also committed to providing our customers with affordable options for large gene synthesis. Our current gene synthesis promotion starts at just $0.19 per base pair, making it more accessible than ever before. We believe that gene synthesis should be available to researchers of all budgets, and we are proud to offer our services at a price point that is accessible to a wide range of customers.

At Synbio Technologies, we are excited to be leading the way in large gene synthesis. With our state-of-the-art Syno® Platform, reliable yeast homologous recombination technology, and commitment to accuracy and affordability, we are able to create genes of any length with ease and precision. Whether you are a researcher working on a complex genetic trait or a company looking to create a new genetically modified product, we are here to help you achieve your goals. Contact us today to learn more about how we can help you with your large gene synthesis needs.

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