In recent years, clinical studies have found that tumor cells are highly expressed by immune checkpoint proteins to reduce the intensity of the body’s innate and adaptive immune response while promoting the “Immune Escape” of tumor cells. Therefore, therapeutic monoclonal antibodies that target immune checkpoint proteins have become the latest strategy for cancer treatment. Examples include anti-CTLA-4 antibody (Iplimumab), anti-PD-1 monoclonal antibody (Nivolumab, Pembrolizumab), and anti-PD-L1 monoclonal antibody (Avelumab, Atezolizumab, Durvalumab, etc.).

Synbio Technologies supplies most of the popular immune checkpoint proteins, including CTLA-4, PD-1, PD-L1, CD47, GITR, TIM-3/TIM1, etc.

Partial Products List

Cat # Protein Expression System Size Price ($)
EXH1002 Human PD-L1 with C-His Expi293 1mg $2,381.32
EXH1003 Human LIGHT with C-His Expi293 1mg $2,645.91
EXH1004 Human PD1 with C-hFc Expi293 1mg $2,381.32
EXH1005 Human PD1 with C-His Expi293 1mg $2,381.32
EXH1006 Human ICOS with C-His Expi293 1mg $2,778.21
EXH1007 Human CD40 with C-His Expi293 1mg $1,719.84
EXM1008 Mouse CD40 with C-His Expi293 1mg $2,116.73
EXH1009 Human CD40 Ligand with N-His-Flag Expi293 1mg $2,381.32
EXM1010 Mouse CD40 Ligand with N-hFc Expi293 1mg $2,249.03
EXH1011 Human CD40 Ligand with N-hFc Expi293 1mg $2,381.32
EXH1012 Human OX40/CD134 with C-hFc Expi293 1mg $2,116.73
EXH1013 Human OX40/CD134 with C-His-Avi Expi293 1mg $1,984.44
EXH1014 Human CD47 with C-His Expi293 1mg $2,513.62
EXH1015 Human CD47 with C-hFc Expi293 1mg $2,381.32
EXH1016 Human CD80 with C-hFc Expi293 1mg $2,116.73
EXH1017 Human CTLA-4 with C-His Expi293 1mg $992.22
EXH1018 Human TIM-3 with C-His Expi293 1mg $2,381.32
EXM1019 MouseTIM-3 with C-His Expi293 1mg $2,116.73
EXH1020 Human TIGIT with C-His Expi293 1mg $2,579.77
EXH1021 Human GITR with C-His Expi293 1mg $2,381.32
EXM1022 Mouse GITR with C-His Expi293 1mg $2,381.32
EXH1023 Human SIRP alpha with C-His Expi293 1mg $2,381.32
EXH1024 Human CD86 with C-His-Avi Expi293 1mg $1,984.44
EXH1025 Human 4-1BB with C-His Expi293 1mg $2,778.21
EXH1026 Human CD137L with N-hFc Expi293 1mg $2,910.51
EXH1027 Human VISTA with C-His Expi293 1mg $2,116.73
EXM1028 Mouse VISTA with C-His Expi293 1mg $2,116.73
EXH1029 Human BTLA with C-His-Avi Expi293 1mg $2,910.51
EXH1030 Human ICOSLG with C-His-Avi Expi293 1mg $1,455.25
EXH1031 Human CD155 with C-hFc Expi293 1mg $2,116.73
EXH1032 Human CD155 with C-His-Avi Expi293 1mg $2,116.73
EXH1033 Human PD-L2 with C-His-Avi Expi293 1mg $1,918.29
EXH1034 Human B7-H3 with C-His Expi293 1mg $2,116.73
EXH1035 Human CD70 with N-hFc Expi293 1mg $1,455.25

*If you don’t find your desired recombinant protein products in the list, please contact quote@synbio-tech.com

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